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S100A4, aa1-101, Recombinant, Human, His-Tag (S100 calcium-binding protein A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, Metastasin)

Cat no: S0051-83K

S100A4, aa1-101, Recombinant, Human, His-Tag (S100 calcium-binding protein A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98, Metastasin)

S100A4, also known as S100 calcium-binding protein A4, belongs to the S100 super-family of proteins containing 2 EF-hand calcium binding domains. This protein is ubiquitously overexpressed and is localized in the cytoplasm and/or nucleus. S100A4 may play a role in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of the S100A4 gene have been implicated in tumor metastasis. \n\nSource:\nRecombinant human S100A4 protein, fused to His-tag at N-terminus, was expressed in E.coli.\n\nMolecular Weight: 13.8kD (121aa)\n\nSequence of amino acids:\nMGSSHHHHHH SSGLVPRGSH MACPLEKALD VMVSTFHKYS GKEGDKFKLN KSELKELLTR ELPSFLGKRT DEAAFQKLMS NLDSNRDNEV DFQEYCVFLS CIAMMCNEFF EGFPDKQPRK K\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S0051-83K

Size

100ug

Form

Supplied as liquid in 20mM Tris-HCl, pH8.0, 10% glycerol.

Purity

(same/more than)95% (SDS-PAGE)

References

1. Sherbet GV., et al. (2009) Cancer Lett. 280(1):15-30, 2. Ambartsumian N., et al. (1995) Gene. 159(1):125-30.

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