S100A7 (Protein S100-A7, Psoriasin, S100 Calcium-binding Protein A7, PSOR1, S100A7C)

S100A7 is an 11-13kD member of the S101 family, EF-hand superfamily of Ca-binding proteins. It is produced by keratinocytes and exists as both an intracellular and extracellular polypeptide. Intercellularly, it binds to E/FABP and may participate in fatty acid metabolism. Extracellularly, it is both monomeric and heterooligomeric and exhibits antibacterial properties. Human S100A7 is 101aa in length. It contains two EF-hand motifs aa13-48, 50-85, three zinc-binding His residues, one high-affinity Ca-binding site aa63-74 and an overlapping antibacterial sequence aa35-80. There appear to be no meaningful rodent structural orthologs. Human S100A7 is 93aa identical to human S100A15/7A, and the S100A7 gene has a duplication (S100A7B) that is 54aa identical to S100A7.\n\nApplications:\nSuitable for use in immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry: 8-25ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

S0051-85M

Size

100ug

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.

P Type

Mab

Purity

Purified by Protein A/G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes human S100A7. No cross-reactivity with recombinant human S100A1, A2, A4, A6, A8, A9, A10, A11, A14, A16, S100B, S100P, recombinant mouse S100A1, A4, A6, A8, A9, A10, A11, A13, or A16.