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S100B (Protein S100-B, S-100 Protein beta Chain, S-100 Protein Subunit beta, S100 Calcium-binding Protein B)

Cat no: 136956

S100B (Protein S100-B, S-100 Protein beta Chain, S-100 Protein Subunit beta, S100 Calcium-binding Protein B)

S100s are calcium binding proteins and are located in the the cytoplasm and/or nucleus of a variety of cell types. S100B is composed of two beta chains, and is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Some of the extracellular functions of S100B may be mediated by RAGE (receptor for advancedglycation end products). Blood levels of S100B can be used to monitor the extent of brain injury and malignant melanoma.\n\nApplications:\nSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:1000\nImmunohistochemistry: 1:250-1:500\nImmunoprecipitation: 1:40\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

136956

Size

100ul

Applications

IHC, IP, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 40% glycerol.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1. Min-Tsai Liu, Yung-Hui Kuan, Jingwen Wang, Ren

Additional Info

Recognizes human S100B. Species Crossreactivity: mouse and rat.

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