Home  >  Products  >  Salermide (N-?[3-?[[(2-?hydroxy-?1-?naphthalenyl)methylene]amino]phenyl]-?a-?methyl-?benzeneacetamide)
Salermide (N-?[3-?[[(2-?hydroxy-?1-?naphthalenyl)methylene]amino]phenyl]-?a-?methyl-?benzeneacetamide)

Salermide (N-?[3-?[[(2-?hydroxy-?1-?naphthalenyl)methylene]amino]phenyl]-?a-?methyl-?benzeneacetamide)

Cat no: S0057-10

Supplier: United States Biological
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Cell-permeable. Salermide is an inhibitor of SIRT1 and SIRT2. In vitro, Salermide has a stronger inhibitory effect on SIRT2 than on SIRT1. It induces massive apoptosis in tumor cells through reactivation of proapoptotic genes epigenetically repressed exclusively in cancer cells by SIRT1. Molecular Weight: ~394.47 Solubility: DMSO (100mM) Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S0057-10
Size: 5mg
Form: Supplied as a yellow solid.
Purity: Highly Purified (~98%)
References: 1. Lara, E., et al. (2009). Oncogene 28, 781-791.

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