Sarcoglycan-alpha Peptide

The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma - and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with E-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.

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SPECIFICATIONS

Catalog Number

BS5920P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Sarcoglycan-alpha. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q16586

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS5920 Sarcoglycan-alpha pAb.

Alternative Names

Alpha-sarcoglycan; Sarcoglycan alpha; alpha-Sarcoglycan; alpha-SG; SG-alpha; SGalpha; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2; Dystroglycan 2; Dystroglycan2; SGCA; ADL; DAG2;