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SCF, Recombinant, Rat (Stem Cell Factor, Stem Cell Factor Precursor, c-Kit Ligand, DKFZp686F2250, KIT Ligand, KitL, KITLG, KL-1, Mast Cell Growth Factor, MGF, Steel Factor, SF)

Cat no: S0400-07R1

SCF, Recombinant, Rat (Stem Cell Factor, Stem Cell Factor Precursor, c-Kit Ligand, DKFZp686F2250, KIT Ligand, KitL, KITLG, KL-1, Mast Cell Growth Factor, MGF, Steel Factor, SF)

Stem cell factor (SCF) is a type I transmembrane protein and hematopoietic growth factor which acts in synergy with other growth factors, and signals through the receptor tyrosine kinase c-Kit (CD117). The interaction between SCF and c-Kit regulates developmental and functional processes of hematopoietic progenitor cells, mast cells, myelanocytes and germ cells, and plays an important role in follicular development. Studies have also shown that the interaction between SCF and c-Kit is associated with the progression and invasiveness of some tumors, including melanomas.\n\nSource:\nRecombinant rat SCF expressed in E. coli\n\nActivity: \nThe ED50 as determined by the dose-dependent stimulation of the proliferation of the human TF-1 cell line is (same/less than)10 ng/ml, corresponding to a specific activity of (same/more than)1 x10e5 units/mg\n\nApplications:\nSuitable for use in Functional Assays. Other applications not tested. \n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot and store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S0400-07R1

Size

10ug

Form

Supplied as a lyophilized powder. Reconstitute with 100ul sterile dH2O.

Purity

>98% by SDS PAGE and HPLC analysis

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