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SDCBP2, Recombinant, Human, aa1-292, His-Tag (Syndecan Binding Protein, SITAC, SITAC18, ST-2)

Cat no: 138735

SDCBP2, Recombinant, Human, aa1-292, His-Tag (Syndecan Binding Protein, SITAC, SITAC18, ST-2)

SDCBP2 contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. \n\nSource:\nRecombinant protein corresponding to aa1-292 from human SDCBP2 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~34.0kD (315aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSMSSLYPS LEDLKVDQAI QAQVRASPKM PALPVQATAI SPPPVLYPNL AELENYMGLS LSSQEVQESL LQIPEGDSTA VSGPGPGQMV APVTGYSLGV RRAEIKPGVR EIHLCKDERG KTGLRLRKVD QGLFVQLVQA NTPASLVGLR FGDQLLQIDG RDCAGWSSHK AHQVVKKASG DKIVVVVRDR PFQRTVTMHK DSMGHVGFVI KKGKIVSLVK GSSAARNGLL TNHYVCEVDG QNVIGLKDKK IMEILATAGN VVTLTIIPSV IYEHMVKKLP PVLLHHTMDH SIPDA\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138735

Size

50ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.15M sodium chloride, 1mM DTT, 10% glycerol.

Purity

~95% (SDS-PAGE)

References

1. Zimmermann, P. (2006) Biochim. Biophys. Acta 1761(8), 947-956 2. Koroll,M., (2001) J. Biol. Chem. 276(14), 10646-10654.

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