Home  >  Products  >  SDF-1 (Stromal Cell-derived Factor 1, hSDF-1, C-X-C Motif Chemokine 12, Intercrine Reduced in Hepatomas, IRH, hIRH, Pre-B Cell Growth-stimulating Factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B, SDF-1-beta, SDF-1-alpha)
SDF-1 (Stromal Cell-derived Factor 1, hSDF-1, C-X-C Motif Chemokine 12, Intercrine Reduced in Hepatomas, IRH, hIRH, Pre-B Cell Growth-stimulating Factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B, SDF-1-beta, SDF-1-alpha)

SDF-1 (Stromal Cell-derived Factor 1, hSDF-1, C-X-C Motif Chemokine 12, Intercrine Reduced in Hepatomas, IRH, hIRH, Pre-B Cell Growth-stimulating Factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B, SDF-1-beta, SDF-1-alpha)

Cat no: S7975-14E

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
SDF1 is a 93aa cytokine belonging to the intercrine alpha (chemokine CxC) family and consisting of 4 conserved cysteines which form 2 disulfide bonds that activate leukocytes and are induced by proinflammatory stimuli like lipopolysaccharide, TNF or IL1. Two splice forms have been identified, SDF-1 alpha and SDF-1 beta. It is involved in astrocyte division, MAP kinase signal transduction and also trigges protein kinase C, zeta phosphorylation, translocation to the plasma membrane and kinase activity. It functions as an autocrine and paracrine mucosal signaling network regulating the epithelial barrier to withstand injury and mediate repair following damage. It induces MMP-13 expression in human chondrocytes and may influence tumor progression. It is expressed in myocardium, bone marrow and skeletal muscle. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:100-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S7975-14E
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Size: 100ul
Form: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Serum
References: 1. Moyer, RA. et al. Lab. Invest. 87:807-817 (2007). 2. Chiu, YC. et al. Mol. Pharmacol. 72:695-703 (2007). 3. Wald, O. et al. J. Immunol. 177:6983-6989 (2006).
Additional info: Recognizes human SDF-1. Species sequence homology: bovine, canine, equine, mouse, rat.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave