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SecB, 1-155aa, Recombinant, E.coli (Protein export chaperone, ECK3599, JW3584)

Cat no: S0579-23

SecB, 1-155aa, Recombinant, E.coli (Protein export chaperone, ECK3599, JW3584)

SecB, a remarkable chaperone involved in protein export, binds diverse ligands rapidly with high affinity and low specificity. It plays a crucial role during protein export via the general secretory pathway by modulating the partitioning of precursors between folding or aggregation and delivery to the membrane-bound translocation apparatus. SecB has the potential to participate in functions outside of export acting as a general nonspecific chaperone to provide buffering capacity of the nonnative state of proteins in the cytosolic pool. \n\nSource:\nRecombinant E.coli SecB protein, expressed in E.coli\n\nMolecular Weight: 17.2kD (155aa)\n\nSequence of amino acids:\nMSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ LADDVYEVVL RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA YCPNILFPYA RECITSMVSR GTFPQLNLAP VNFDALFMNY LQQQAGEGTE EHQDA \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at 20 or 70 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S0579-23

Size

100ug

Form

Supplied as liquid in 20mM Tris-HCl, pH 8.0, 10% glycerol.

Purity

(same/more than)95% (SDS-PAGE)

References

1. Driessen AJ., et al. (2008), Annu Rev Biochem. 77:643-67. 2. Bechtluft P., et al. (2007). Science. 318(5855):1458-61.

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