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Senkirkine

Cat no: 020896


Supplier: United States Biological
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Senkirkine is a hepatotoxic pyrrolizidine alkaloid. Studies show that Senkirkine has carincogenic activity as it induced chromosomal aberrations in cultured mammalian cells as well as hepatic tumors in rats.
Catalogue number: 020896
Size: 1mg
Alternative names: (1R,4Z,6R,7R)-4-Ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione; 12-Hydroxy-4-methyl-4,8-secosenecionan-8,11,16-trione; 2,3,5,7a-Tetrahydro-1,7a-dihydroxy-7-(hydroxymethyl)-4-methyl-1H-pyrrolizinium hydroxide Inner Salt Cyclic Diester with Senecic Acid; [1R-(1R*,4Z,6R*,7R*)]-4-Ethylidene-7-hydroxy-6,7,14-trimethyl-2,9-dioxa-14-azabicyclo[9.5.1]heptadec-11-ene-3,8,17-trione; NSC 89945; Renardin; Renardine; Senkirkin;
References: Culvenor, C. et al.: Aus. J. Chem., 29, 229 (1976); Takanashi, H. et al.: Mutat. Res. Gen. Toxicol. Test., 78, 67 (1980); Hirono, I. et al.: J. Nat. Cancer. Inst., 63, 469 (1979);

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