Home  >  Products  >  SENP6 (SUSP1, Sentrin-specific Protease 6, Sentrin/SUMO-specific Protease SENP6, SUMO-1-specific Protease 1, KIAA0797, SSP1, FKSG6)
SENP6 (SUSP1, Sentrin-specific Protease 6, Sentrin/SUMO-specific Protease SENP6, SUMO-1-specific Protease 1, KIAA0797, SSP1, FKSG6)

SENP6 (SUSP1, Sentrin-specific Protease 6, Sentrin/SUMO-specific Protease SENP6, SUMO-1-specific Protease 1, KIAA0797, SSP1, FKSG6)

Cat no: S0745-03D

Supplier: United States Biological
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Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1), are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin.1,2 However, covalent attachment of UBLs does not result in degradation of the modified proteins.. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more aa following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases such as SUMO1-specific protease 1 (SUSP1) prior to their conjugation to target proteins. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S0745-03D
Reactivities: Human, Mouse, Canine
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Kim KI, Baek SH, Jeon YJ, Nishimori S, Suzuki T, Uchida S, Shimbara N, Saitoh H, Tanaka K, Chung CH. A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs. J Biol Chem. 2000 May 12;275(19):14102-6.
Additional info: Recognizes SENP6. Species sequence homology: Canine, human and mouse.

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