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SERPINL1, Recombinant, Human (Neuroserpin, CLADE I, DKFZp781N13156, Protease Inhibitor 12, PI12, Serine or Cysteine Proteinase Inhibitor Clade I Member 1)

Cat no: S1000-95D

SERPINL1, Recombinant, Human (Neuroserpin, CLADE I, DKFZp781N13156, Protease Inhibitor 12, PI12, Serine or Cysteine Proteinase Inhibitor Clade I Member 1)

SerpinI1, otherwise known as Neuroserpin, is an axonally secreted serine protease inhibitor and member of the Serpin family, predominantly expressed in the brain, which binds to and inactivates plasminogen activators and plasmin. The expression of SerpinI1 during the late stages of embryonic neurogenesis, suggests SerpinI1 may play a role in the formation or reorganization of synaptic connections, and is implicated as a regulator of proteases involved in neuronal migration and synaptic plasticity.\n\nSource:\nPurified recombinant SerpinI1 expressed in E.coli\n\nActivity: \nDetermined by the dose-dependent stimulation of the proliferation of rat C6 cells using a concentration range of 0.3-0.6ug/ml.\n\nApplications:\nSuitable for use in Functional Assays. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nEndotoxin Level: \n(same/less than)1EU/ug\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with 250ul ddH2O. Aliquot and store at -20 degrees C. Reconstituted product is stable for 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S1000-95D

Size

25ug

Reactivities

Hum

Form

Supplied as a lyophilized powder. Reconstitute with 250ul ddH2O.

Purity

(same/less than) 96% by SDS PAGE and HPLC analysis.

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