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SH3GLB1, Recombinant, Human, aa1-365, His-Tag (Endophilin-B1, Bif-1, CGI-61, dJ612B15.2, PPP1R70)

Cat no: 138739

SH3GLB1, Recombinant, Human, aa1-365, His-Tag (Endophilin-B1, Bif-1, CGI-61, dJ612B15.2, PPP1R70)

SH3GLB1, also as known as endophilin-B1, belongs to the endophilin family. Endophilin B1 is a member of the B subgroup of the endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. This protein required for normal outer mitochondrial membrane dynamics. Also it required for coatomer-mediated retrograde transport in certain cells. SH3GLB1 has been shown to interact with SH3GLB2 and Bcl-2-associated X protein. This protein highly expressed in heart, skeletal muscle, kidney and placenta. \n\nSource:\nRecombinant protein corresponding to aa1-365 from human SH3GLB1 at C-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~41.9kD (373aa)\n\nAA Sequence:\nMNIMDFNVKK LAADAGTFLS RAVQFTEEKL GQAEKTELDA HLENLLSKAE CTKIWTEKIM KQTEVLLQPN PNARIEEFVY EKLDRKAPSR INNPELLGQY MIDAGTEFGP GTAYGNALIK CGETQKRIGT ADRELIQTSA LNFLTPLRNF IEGDYKTIAK ERKLLQNKRL DLDAAKTRLK KAKAAETRNS SEQELRITQS EFDRQAEITR LLLEGISSTH AHHLRCLNDF VEAQMTYYAQ CYQYMLDLQK QLGSFPSNYL SNNNQTSVTP VPSVLPNAIG SSAMASTSGL VITSPSNLSD LKECSGSRKA RVLYDYDAAN STELSLLADE VITVFSVVGM DSDWLMGERG NQKGKVPITY LELLNLEHHH HHH\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138739

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.1M sodium chloride, 2mM DTT, 10% glycerol.

Purity

~90% by (SDS-PAGE)

References

1. Pierrat B., et al. (2001) Genomics 71:222-234 2. Modregger J., et al. (2003) J. Biol. Chem. 278:4160-4167.

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