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Sheep anti Human Platelet Glycoprotein IIb/IIIa polyclonal antibody

Sheep anti Human Platelet Glycoprotein IIb/IIIa polyclonal antibody

Cat no: CABT-L518

Supplier: Creative Diagnostics
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Sheep Anti-Human Platelet Glycoprotein IIb/IIIa polyclonal antibody for IEP, ELISA. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Catalogue number: CABT-L518
Reactivities: Human
Hosts: Sheep
Applications: ELISA
Conjugates: Unconjugated
Gene: 3674
Target: ITGA2B
Isotype: IgG
Clonality: Polyclonal
Storage temp: Store between -10 and -20°C. Product will become viscous but will not freeze. Avoid storage in frost-free freezers. Keep vial tightly capped. Allow product to warm to room temperature and gently mix before use.

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