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SHH, Recombinant, Mouse (Sonic Hedgehog Protein, HHG-1, Hhg1)

Cat no: S1012-96N

SHH, Recombinant, Mouse (Sonic Hedgehog Protein, HHG-1, Hhg1)

Recombinant Mouse Sonic Hedgehog is a member of a small group of secreted proteins that are essential for development in both vertebrates and invertebrates. Three mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology. The Mouse Sonic Hedgehog is 99% homologous to the human gene. Cysteine at position 25 has been substituted with Ile. Mouse SHH is a non-glycosylated polypeptide consisting of 176aa with a molecular weight of 19.8kD.\n\nRecombinant corresponding to mouse Sonic Hedgehog expressed in E. coli.\n\nAmino Acid Sequence:\nMIIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKITRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG\n\nBiological Activity: \nMouse SHH is fully biologically active when compared to standard. Determined by its

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SPECIFICATIONS

Catalog Number

S1012-96N

Size

25ug

Form

Supplied as a lyophilied powder from 10mM sodium phosphate buffer, pH 7.5. Reconstitute with sterile ddH2O to 0.1-0.5mg/ml. Add 0.1% BSA or HSA for long term storage.

Purity

~97% (SDS-PAGE, HPLC). Endotoxin: <0.01ng/ug

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