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SHP-2 (PTP-2C) Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251601

SHP-2 (PTP-2C) Antibody

Tyrosine-protein phosphatase non-receptor type 11 (SHP-2 (PTP-2C)) Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Defects in PTPN11 are the cause of LEOPARD syndrome type 1 (LEOPARD1). This is an autosomal dominant disorder allelic with Noonan syndrome. The acronym LEOPARD stands for lentigines, electrocardiographic conduction abnormalities, ocular hypertelorism,Porcineulmonic stenosis, abnormalities of genitalia, retardation of growth, and deafness.

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SPECIFICATIONS

Catalog Number

251601

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SHP-2 (PTP-2C).

Isotype

Rabbit Ig

Accession

Q06124

Additional Info

SHP-2; PTP-2C; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 2C; Protein-tyrosine phosphatase 1D; PTP-1D; SH-PTP3; SH-PTP2; Shp2; PTPN11; PTP2C; SHPTP2

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