SHP-2 (PTP-2C) Antibody

Cat no: 251601

Supplier: ABBIOTEC

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Description
Additional Information

Tyrosine-protein phosphatase non-receptor type 11 (SHP-2 (PTP-2C)) Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Defects in PTPN11 are the cause of LEOPARD syndrome type 1 (LEOPARD1). This is an autosomal dominant disorder allelic with Noonan syndrome. The acronym LEOPARD stands for lentigines, electrocardiographic conduction abnormalities, ocular hypertelorism,Porcineulmonic stenosis, abnormalities of genitalia, retardation of growth, and deafness.

Catalogue number:	251601
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q06124
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SHP-2 (PTP-2C).
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	SHP-2; PTP-2C; Tyrosine-protein phosphatase non-receptor type 11; Protein-tyrosine phosphatase 2C; Protein-tyrosine phosphatase 1D; PTP-1D; SH-PTP3; SH-PTP2; Shp2; PTPN11; PTP2C; SHPTP2