A competitive inhibitor of HMG-CoA reductase. A metabolite of Simvastin
Melting Point: 150-152C
Solubility:
DMSO, Methanol
Stability:
Moisture and temperature sentitive
Atmosphere:
Inert gas
Method for determining Identity:
HNMR Spectroscopic Analysis ; conform to srtucture
TLC Conditions:
SiO2: Chloromethane: Methanol: NH4OH; 20: 6; 1; Visualized with UV and AMCS; Single spot; Rf=0.4
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.