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Sirtuin 1, Recombinant, Mouse (His) (Sirt1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2alpha, Sir2l7)

Sirtuin 1, Recombinant, Mouse (His) (Sirt1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2alpha, Sir2l7)

Cat no: 045290

Supplier: United States Biological
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Sirtuin 1 (SIRT1) is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Sirtuin 1 emerged as critical regulator of longevity and aging in several model organisms. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Sirtuin 1 has been suggested as potential biomarker for tumorigenesis. Sequence: Mouse sirtuin 1 (aa 2-737) is fused at the N-terminus to a His-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Working aliquots are stable for up to 3 months when stored at -20 degrees C.
Catalogue number: 045290
Size: 10ug
Form: Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Purity: >90% (SDS-PAGE)
Alternative names: Sirt1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2alpha, Sir2l7

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