Home  >  Products  >  SIT1, Recombinant, Human, aa1-196, His-tag (Signaling Threshold-regulating Transmembrane Adapter 1, SHP2-interacting Transmembrane Adapter Protein, Suppression-inducing Transmembrane Adapter 1, gp30/40, SIT)
SIT1, Recombinant, Human, aa1-196, His-tag (Signaling Threshold-regulating Transmembrane Adapter 1, SHP2-interacting Transmembrane Adapter Protein, Suppression-inducing Transmembrane Adapter 1, gp30/40, SIT)

SIT1, Recombinant, Human, aa1-196, His-tag (Signaling Threshold-regulating Transmembrane Adapter 1, SHP2-interacting Transmembrane Adapter Protein, Suppression-inducing Transmembrane Adapter 1, gp30/40, SIT)

Cat no: 029699

Supplier: United States Biological
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SIT1, negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. This protein involved in positive selection of T-cells. Source: Recombinant corresponding to aa1-196 from human SIT1, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MHLSQWTRGR SRSHPGQGRS GESVEEVPLY GNLHYLQTGR LSQDPEPDQQ DPTLGGPARA AEEVMCYTSL QLRPPQGRIP GPGTPVKYSE VVLDSEPKSQ ASGPEPELYA SVCAQTRRAR ASFPDQAYAN SQPAAS Molecular Weight: ~16.9kD (MALDI-TOF) Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 029699
Size: 10ug
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 20% glycerol.
Purity: ~90% (SDS-PAGE)
References: 1. Marie-Cardine A., et al. (1999) J. Exp. Med. 189:1181-1194 2. Pfrepper K., et al. (2001) Eur. J. Immunol. 31:1825-1836.

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