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SIX1, Recombinant, Human, aa1-284, His-Tag (Homeobox Protein SIX1, BOS3, DFNA23, TIP39)

Cat no: 138741

SIX1, Recombinant, Human, aa1-284, His-Tag (Homeobox Protein SIX1, BOS3, DFNA23, TIP39)

SIX1, also known as homeobox protein SIX1, is a member of the SIX gene family. It encodes protein that is characterized by a divergent DNA-binding homeodomain and an upstream SIX domain, which may be involved both in determining DNA-binding specificity and in mediating protein-protein interactions. It has been shown to play roles in vertebrate and insect development or has been implicated in maintenance of the differentiated state of tissues. \n\nSource:\nRecombinant protein corresponding to aa1-284 from human SIX1 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~34.7kD (308aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSH YKILESHQFS PHNHPKLQQL WLKAHYVEAE KLRGRPLGAV GKYRVRRKFP LPRTIWDGEE TSYCFKEKSR GVLREWYAHN PYPSPREKRE MSMLPS FGFTQEQVAC VCEVLQQGGN LERLGRFLWS LPACDHLHKN ESVLKAKAVV AFHRGNFREL LAEATGLTTT QVSNWFKNRR QRDRAAEAKE RENTENNNSS SNKQNQLSPL EGGKPLMSSS EEEFSPPQSP DQNSVLLLQG NMGHARSSNY SLPGLTASQP SHGLQTHQHQ LQDSLLGPLT SSLVDLGS\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138741

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 2M urea, 10% glycerol.

Purity

~85% (SDS-PAGE)

References

1. Ruf RG. et al. (2004) Proc Natl Acad Sci U S A. 101(21):8090-8095. 2. Oliver G. et al. (1995) Development. 121(3):693-705.

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