Skp2 Antibody

Cat no: 251467

Supplier: ABBIOTEC

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Description
Additional Information

Skp2 (S-phase kinase-associated protein 2) is a substrate recognition component of a SCF (SKP1-CUL1-F-bo, Xenopus/Amphibian, protein) E3 ubiquitin-protein ligase comple, Xenopus/Amphibian, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Skp2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition.

Catalogue number:	251467
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q13309
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Skp2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	Skp2; S-phase kinase-associated protein 2; F-bo, Xenopus/Amphibian, protein Skp2; Cyclin A/CDK2-associated protein p45; p45skp2; F-bo, Xenopus/Amphibian,/LRR-repeat protein 1; FB, Xenopus/Amphibian,L1