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SLAMF6, Recombinant, Human, aa22-226, His-Tag (SLAM Family Member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000)

Cat no: 138743

SLAMF6, Recombinant, Human, aa22-226, His-Tag (SLAM Family Member 6, CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000)

SLAM family member 6, also known as SLAMF6, belongs to the SLAM family of immune cell receptors. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SLAMF6 is expressed on NK-, T-, and B cells. It exhibits homotypic interactions and can associate with adaptor molecules such as SAP to modulate immune cell functions. \n\nSource:\nRecombinant protein corresponding to aa22-226 from human SLAMF6 at N-terminal, fused to His-tag expressed in E.coli. \n\nMolecular Weight: \n~25.5kD (228aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSQSSLTPL MVNGILGESV TLPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKM\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

138743

Size

100ug

Form

Supplied as a liquid in 20mM tris-HCl buffer, pH 8.0, 0.4 urea, 10% glycerol.

Purity

~85% (SDS-PAGE)

References

1. Freeman G J., et al. (1991) J EXP Med. 174:625-631. 2. Aversa G., et al. (1997) Immunol Cell Biol. 75:202-205.

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