SLC22A6 pAb

Cat no: BS6781

Supplier: Bioworld Technology, Inc.

0 reviews | Write a Review Pencil

Description
Additional Information

The organic anion transporter (OAT) family of proteins mediate the secretion of exogenous and endogenous levels of metabolites from tissues throughout the body. OAT1 (organic anion transporter 1), a 563 amino acid protein, and OAT3 (organic anion transporter 3), a 542 amino acid protein, are two members of the OAT family and are highly expressed in kidneys. Localized specifically to the basolateral membrane, OAT1 and OAT3 are involved in the elimination of toxic organic anions, such as benzylpenicillin and cimetidine, from proximal renal tubules. Via their ability to remove anions from renal tissues, OAT1 and OAT3 are able to regulate the amount of toxins within the kidneys. Additionally, OAT1 functions as an organic anion exchanger that couples the uptake of one organic anion molecule with the efflux of one endogenous levels of dicarboxylic acid molecule, such as ketoglutarate. Four isoforms of OAT1 and three isoforms of OAT3 are expressed due to alternative splicing events.

Catalogue number:	BS6781
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q4U2R8
Dilutions:	WB: 1:500~1:2000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Recombinant full length Human SLC22A6.
Species:	SLC22A6 pAb detects endogenous levels of SLC22A6 protein.
Molecular weight:	~ 62 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	hOAT1; hPAHT; hROAT1; Organic anion transporter 1; PAH transporter; PAHT; Para aminohippurate transporter; Renal organic anion transporter 1; ROAT1; S22A6; SLC22A6; Solute carrier family 22 (organic anion transporter) member 6; Solute carrier family 22 member 6;
Additional info:	For research use only, not for use in diagnostic procedure.

See Full Product Listings >

SLC22A6 pAb

Cat no: BS6781

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Bioworld Technology, Inc.




By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*