SLC6A1 pAb

Cat no: BS5726

Supplier: Bioworld Technology, Inc.

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GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA ((gamma)-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R(alpha)1-6, GABAA R (beta)1-3, GABAA R(gamma)1-3, GABAA R(delta), GABAA RE, GABAA R?1 and GABAA R?2. The GABAB family is composed of GABAB R1(alpha) and GABAB R1(beta). GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.

Catalogue number:	BS5726
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Western Blot
Size:	100ug/100ul
Swiss prot:	P30531
Dilutions:	WB: 1:500~1:1000 ICC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 431-476 of Human SLC6A1.
Species:	SLC6A1 pAb detects endogenous levels of SLC6A1 protein.
Molecular weight:	~ 67 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	Sodium- and chloride-dependent GABA transporter 1; GAT-1; Solute carrier family 6 member 1; GABATR; GABT1; GAT1; GABA T-1; GABA T1; GABAT1;
Additional info:	For research use only, not for use in diagnostic procedure.

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SLC6A1 pAb

Cat no: BS5726

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