Smad2/3 Antibody

Cat no: 251894

Supplier: ABBIOTEC

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Description
Additional Information

SMAD family member 2 (SMAD2/3) is receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. SMAD2/3 binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 comple, Xenopus/Amphibian,, activates transcription. SMAD2/3 acts as a tumor suppressor in colorectal carcinoma.

Catalogue number:	251894
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	Q15796; P84022
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Smad2/3.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	SMAD2; Mothers against decapentaplegic homolog 2; Mothers against DPP homolog 2; Mad-related protein 2; hMAD-2; MADH2; MADR2; SMAD3; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; hMAD-3; SMAD family member 3; Smad3; hSMAD3; JV15-2; SMAD3; MADH3