logo
logo
Advertisehere
MtoZ Horizontal banner
MtoZ Biolabs

Latest promotion FROM:

MtoZ Biolabs
View promotion
Smad7 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251212

Smad7 Antibody

Mothers against decapentaplegic homolog 7 (Smad7) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members. Smad7 has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Smad7 functions as an adapter to recruit SMURF2 to the TGF-beta receptor comple, Xenopus/Amphibian,. Smad7 also acts by recruiting the PPP1R15A-PP1 comple, Xenopus/Amphibian, to TGFBR1, which promotes its dephosphorylation. Genetic variations in Smad7 influence susceptibility to colorectal cancer type 3 (CRCS3). Colorectal cancer consists of tumors or cancer of either the colon or rectum or both.

Prices direct from ABBIOTEC

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

251212

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Bov, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Smad7.

Isotype

Rabbit Ig

Accession

O15105

Additional Info

Smad7; Mothers against decapentaplegic homolog 7; Mothers against DPP homolog 7; hSMAD7; MADH7

SUPPLIER INFO

ABBIOTEC

Latest promotions

Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...

New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...

As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....

It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...

We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!

10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...

For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...

Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...

Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...

Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...

Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...