A metabolite of Irinotecan, a DNA topoisomerase inhibitor.
Melting Point:
218-221 degrees C
Solubility:
DMSO
Method for Determining Identity:
1H NMR Spectroscopic Analysis and Specific Rotation.
TLC Conditions:
SiO2; Chloroform; Methanol; NH4OH; 9: 1: 0.3; Visualized with UV (280NM) and AMCS; Rf=0.3
Specific Rotation:
-22.6 (c=1, DMSO)
Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.