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SNCA, aa1-140, Recombinant, Mouse (Alpha-synuclein, Alpha-synuclein, MGC110988, NACP, Non-A4 component of amyloid precursor, Non-A beta component of AD amyloid, PARK1, PARK4, PD1)

Cat no: S9500-31D

SNCA, aa1-140, Recombinant, Mouse (Alpha-synuclein, Alpha-synuclein, MGC110988, NACP, Non-A4 component of amyloid precursor, Non-A beta component of AD amyloid, PARK1, PARK4, PD1)

Alpha-Synuclein, also known as SNCA, an acidic neuronal protein of 140aas, is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. alpha-Synuclein has been suggested to be implicated in the pathogenesis of Parkinson. \n\nSource:\nRecombinant corresponding to aa1-140 mouse SNCA his tagged, expressed in E.coli. \n\nAA Sequences: \nMDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S9500-31D

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 10% glycerol.

Purity

~95% (SDS-PAGE)

References

1. Ueda K., et al. (1993) Proc. Natl. Acad. Sci. USA 90:11282-11286 2. Kim J., et al. (1997) Molecules and Cells 7:78-83 3. Jakes R., et al. (1994) FEBS lett. 345:27-32.

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