Species: human - female, 40 years old, Mongoloid
Abnormal genes: HPV 16, E7 gene codon 647, AAT->AGT(Asn to Ser)
Virus: HPV type 16
Histopathology: carcinoma, squamous cell; stage IIA (FIGO)
Note: HPV 16, E1 gene deleted, E2 gene intact; HPV 16 was presumably integrated into chromosome; HPV 16 was not detectably by Southern blot analysis; E6/E7 gene of HPV 16 was expressed by Northern analysis.
p53 mutation: wild type
Kras codon 12: wild type