Species: human - female, 57 years old, Mongoloid
Abnormal genes: HPV16, E7 gene, codon 647, AAT->AGT (Asn to Ser)
Virus: HPV type 16
Histopathology: carcinoma, squamous cell; stage IIB (FIGO)
Note: HPV16, E1 gene, intact, E2 gene, deleted; HPV 16 was presumably integrated into chromosome; HPV16 was not detectable by Southern blot analysis; E6/E7 gene of HPV16 was expressed by Northern analysis.
p53 mutation: wild type
Kras codon 12: wild type