Home  >  Products  >  SNX18 (Sorting Nexin 18, Sorting Nexin-18, FLJ11997, FLJ32560, FLJ61062, MGC150827, MGC150829, SH3 and PX Domain-containing Protein 3B, SH3PXD3B, SH3PX2, Sorting Nexin-associated Golgi Protein 1, SNAG1)
SNX18 (Sorting Nexin 18, Sorting Nexin-18, FLJ11997, FLJ32560, FLJ61062, MGC150827, MGC150829, SH3 and PX Domain-containing Protein 3B, SH3PXD3B, SH3PX2, Sorting Nexin-associated Golgi Protein 1, SNAG1)

SNX18 (Sorting Nexin 18, Sorting Nexin-18, FLJ11997, FLJ32560, FLJ61062, MGC150827, MGC150829, SH3 and PX Domain-containing Protein 3B, SH3PXD3B, SH3PX2, Sorting Nexin-associated Golgi Protein 1, SNAG1)

Cat no: S1014-97Q2

Supplier: United States Biological
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May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S1014-97Q2
Reactivities: Human
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Teasdale RD, Loci D, Houghton F, Karlsson L, Gleeson PA. A large family of endosome-localized proteins related to sorting nexin 1. Biochem J. 2001 Aug 15;358(Pt 1):7-16.
Additional info: Recognizes human SNX18.

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