
Prices direct from Biomatik Corporation
Quick response times
Exclusive Biosave savings/discounts
SPECIFICATIONS
Price
323.00 USD
Catalog Number
CAC07311
Size
100 micro g
Applications
WB
Hosts
Rabbit
Conjugates
Unconj
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Target
Socs3
Clonality
Polyclonal
Storage Temp
Aliquot and store at -20 degrees C. Minimize freezing and thawing.
Research Area
For research use only. Not for diagnostic procedures.
Shipping Temp
Blue ice
Additional Info
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. Binding to JAK2 inhibits its kinase activity. Suppresses fetal liver erythropoiesis. Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells. Regulates IL-6 signaling in vivo. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize IL6ST (By similarity).
Alternative Names
Suppressor of cytokine signaling 3,SOCS-3,Socs3,Cish3,Cytokine-inducible SH2 protein 3
More from Biomatik Corporation
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Applications
ELISA
Reactivities
Hum
Latest promotions
Spend less time on DNA cleanup so you can do more science. The MSB Spin PCRapace is the fastest way to purify your DNA from PCR, restriction digestion, and...
As an incentive to qualify our BSA, we are offering a 20% discount when you purchase your first 100g, 500g or 1000g of any grade of Bovine Serum Albumin....
New brilliant antibodies, and new lower prices!For flow cytometry reagents in general, \"bright is better.\" The violet-excitable BD Horizon™ BV421 and...
It is not every day that you are given something for nothing. We are giving away additional spectrophotometer software.Cecil Instruments have enhanced the...
For the past decade scientists have extensively used ATS secondary toxin conjugates to make their own targeted toxins for in vitro use.The ability to combine...
We're so sure that you'll prefer Cayman Assay kits over your present brand that we're willing to give you a free assay kit to prove it!
10% Discount on 2 Rabbit Polyclonal Antibody Service. With over 20 years experience, SDIX has developed into the premier US custom antibody producer,...
Did your supplier increase the price of Fetal Bovine Serum? Did they substitute the US Origin with USDA? Well say no more! Innovative Research is still...
Bulk Cytokines with Custom Vialing.20 - 50% off cytokines, growth factors, chemokines and more...For a limited time Cell Sciences is offering substantial...
Are you planning to have a customised antibody made for your research?Since 2000, Everest has been producing a catalog containing thousands of affinity...
Jenway’s 73 series spectrophotometer range provides four models with a narrow spectral bandwidth of 5nm and an absorbance range of –0.3 to 2.5A,...
Top suppliers
United States Biological
230753 products
Carl Zeiss Microscopy
27 products
Promega Corporation
11 products
Panasonic Healthcare Company
5 products
Life Technologies
1 products
Nikon Instruments Europe
11 products
Olympus Europa Holding GmbH
3 products
Leica Microsystems, Inc.
10 products
GE Healthcare Life Sciences
2 products
Tecan Trading AG
19 products
Beckman Coulter, Inc.
1 products
AB SCIEX
3 products
BD (Becton, Dickinson and Company)
1 products
RANDOX TOXICOLOGY
5 products
Randox Food Diagnostics
6 products


















