Somatostatin 28 (Somatostatin-28, Growth Hormone Release Inhibiting Factor, Somatostatin Precursor, SMST, SST)

Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF) is widely distributed throughout the body. It has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids. Somatostatin is an important regulator of endocrine and nervous system function. It exerts its biologic actions by binding to specific high affinity receptors on the cell surface. Somatostatin has also been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid.\n\nApplications: \nSuitable for use in Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: pancreas and colon samples\n\nCellular Localization: Secreted\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. \n

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SPECIFICATIONS

Catalog Number

S5331-30K

Size

50ul

Applications

IF, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat, Bov, Can, Ch/Bird, Fel, GP, Prc, Sheep

Form

Whole serum

P Type

Pab

Purity

Whole antisera

Isotype

IgG

Additional Info

Recognizes human Somatostatin 28 on pancreas and colon samples and also on somatostatinergic neurons. Does not crossreact with somatostatin 14. Species Crossreactivity: Mouse, Rat, Chicken, bovine, canine, Cat, Guinea pig, Pig and Sheep.