Home  >  Products  >  SORBS1 (Sorbin and SH3 Domain-containing Protein 1, Ponsin, SH3 Domain Protein 5, SH3P12, c-Cbl-associated Protein, CAP, KIAA0894, KIAA1296, SH3D5)
SORBS1 (Sorbin and SH3 Domain-containing Protein 1, Ponsin, SH3 Domain Protein 5, SH3P12, c-Cbl-associated Protein, CAP, KIAA0894, KIAA1296, SH3D5)

SORBS1 (Sorbin and SH3 Domain-containing Protein 1, Ponsin, SH3 Domain Protein 5, SH3P12, c-Cbl-associated Protein, CAP, KIAA0894, KIAA1296, SH3D5)

Cat no: S5350-75H

Supplier: United States Biological
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Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Immunohistochemistry (Paraffin): 2.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S5350-75H
Reactivities: Human, Mouse, Rat, Porcine
Hosts: Goat
Applications: ELISA, Immunohistochemistry
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Ribon V, Printen JA, Hoffman NG, Kay BK, Saltiel AR. A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Mol Cell Biol. 1998 Feb;18(2):872-9.
Additional info: Recognizes human SORBS1. Species sequence homology: Mouse, porcine and rat.

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