SORL1 (7D7B) Antibody

Cat no: 252737

Supplier: ABBIOTEC

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Description
Additional Information

SORL1 (Sortilin-related receptor, LA repeats containing) is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytosis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. SorLA is e, Xenopus/Amphibian,pressed mainly in brain (cerebral corte, Xenopus/Amphibian,, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.

Catalogue number:	252737
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	Q92673
Antigen:	Purified recombinant fragment of SORL1(aa2159-2214) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	7D7B11
Additional info:	Sortilin-related receptor; Low-density lipoprotein receptor relative with 11 ligand-binding repeats; LDLR relative with 11 ligand-binding repeats; LR11; SorLA-1; Sorting protein-related receptor containing LDLR class A repeats; SorLA; SORL1; C11orf32