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SP-A (35kD pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-4)

Cat no: 145210

SP-A (35kD pulmonary surfactant-associated protein, Alveolar proteinosis protein, Collectin-4)

Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14.1Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.2\n\nUniProt Number:\nQ8IWL2\n\nGene ID:\nSFTPA1\n\nApplications:\nSuitable for use in Western Blot.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Handling:\nStore at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term.\nAvoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

145210

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Rat

Form

Supplied as a liquid. Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

1?Moore, K. J., D'Amore-Bruno, M. A., Korfhagen, T. R., Glasser, S. W., Whitsett, J. A., Jenkins, N. A., Copeland, N. G. Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics 12: 388-393, 1992.\n2?Ramet, M., Lofgren, J., Albo, O.-P., Hallman, M. Surfactant protein-A gene locus associated with recurrent otitis media. J. Pediat. 138: 266-268, 2001.

Additional Info

Recognizes human and rat SP-A. No crossreactivity with other proteins.

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