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Spasmolysin Peptide

Spasmolysin Peptide

Cat no: BS60387P

Supplier: Bioworld Technology, Inc.
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Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing and protection of the gastrointestinal epithelia. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. SP (spasmolytic polypeptide), also designated Trefoil factor 2 (TFF2) precursor, is a trefoil protein that functions to inhibit gastrointestinal motility and gastric acid secretion. SP may also act as a structural component of the gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains. A downregulation of SP expression is associated with primary gastric cancer, and a progressive loss of this protein is likely to be involved in the early stage of the multi-step gastric carcinogenesis pathway.
Catalogue number: BS60387P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q03403
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Spasmolysin. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Trefoil factor 2; Spasmolysin; Spasmolytic polypeptide; SP; TFF2; SML1
Additional info: This peptide can be used with studies using BS60387 Spasmolysin pAb.

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