Spectrin alpha/beta Antibody

Cat no: 251797

Supplier: ABBIOTEC

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Description
Additional Information

Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. Spectrin associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Defects in spectrin are the cause of elliptocytosis type 2 (EL2). EL2 is a Rhesus-unlinked form of hereditary elliptocytosis, a genetically heterogeneous, autosomal dominant hematologic disorder. EL2 is characterized by variable hemolytic anemia and elliptical or oval red cell shape.

Catalogue number:	251797
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 mg
Accession:	P02549; P11277
Antigen:	Human erythrocyte spectrin.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Additional info:	Spectrin alpha chain, erythrocyte; Erythroid alpha-spectrin; SPTA1; SPTA; Spectrin beta chain, erythrocyte; Beta-I spectrin; SPTB; SPTB1