Home  >  Products  >  SPFH2 (Erlin-2, Endoplasmic Reticulum Lipid Raft-associated Protein 2, Stomatin-prohibitin-flotillin-HflC/K Domain-containing Protein 2, SPFH Domain-containing Protein 2, C8orf2, ERLIN2, UNQ2441/PRO5003/PRO9924)
SPFH2 (Erlin-2, Endoplasmic Reticulum Lipid Raft-associated Protein 2, Stomatin-prohibitin-flotillin-HflC/K Domain-containing Protein 2, SPFH Domain-containing Protein 2, C8orf2, ERLIN2, UNQ2441/PRO5003/PRO9924)

SPFH2 (Erlin-2, Endoplasmic Reticulum Lipid Raft-associated Protein 2, Stomatin-prohibitin-flotillin-HflC/K Domain-containing Protein 2, SPFH Domain-containing Protein 2, C8orf2, ERLIN2, UNQ2441/PRO5003/PRO9924)

Cat no: S5402-01A

Supplier: United States Biological
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Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Western Blot: 0.3-1ug/ml, observed in human breast lysates and in lysates of breast cancer on ~43kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S5402-01A
Reactivities: Human, Rat
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Garcia MJ, Pole JC, Chin SF, Teschendorff A, Naderi A, Ozdag H, Vias M, Kranjac T, Subkhankulova T, Paish C, Ellis I, Brenton JD, Edwards PA, Caldas C. A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. Oncogene. 2005 Aug 4;24(33):5235-45.
Additional info: Recognizes human ERLIN2. Species sequence homology: Rat.

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