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sRANKL, Recombinant, Human (soluble RANK Ligand, Receptor Activator of NFkB Ligand)

Cat no: R1076-03A

sRANKL, Recombinant, Human (soluble RANK Ligand, Receptor Activator of NFkB Ligand)

Source: \nRecombinant corresponding to human sRANKL expressed in E. coli.\n\nMolecular Weight: \n~20kD (corresponding to the full length of the TNF-like extracellular domain)\n\nBiological Activity: \nED50 <10ng/ml. The biological activity was determined by measuring the dose-dependent stimulation of IL-8 production by isolated human PBMCпїЅs. sRANKL, also known as ODF, TRANCE and TNF superfamily member 11, is a member of the TNF ligand superfamily. The receptor for sRANKL is RANK (Receptor Activator of NF-KappaB), a member of the TNFR family identified as a dendritic cell membrane protein. sRANKL influences dendritic cellsпїЅ ability to stimulate T-cells. \n\nEndotoxin: ~0.1ng/ug\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

R1076-03A

Size

10ug

Form

Supplied as a lyophilized powder in 5mM Tris, pH 7.6, and 50mM sodium chloride. Reconstitute with sterile dH2O to 0.1-1mg/ml.

Purity

~98% (SDS-PAGE, HPLC)

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