SRC (4F1E) Antibody

Cat no: 252767

Supplier: ABBIOTEC

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Description
Additional Information

c-Src (Proto-oncogene tyrosine-protein kinase Src) is a non-receptor protein tyrosine kinase. It plays pivotal roles in numerous cellular processes such as proliferation,Mouse,igration and transformation. In concert with PTK2Bovine, c-Src plays an important role in osteoclastic bone resorption. Both the formation of a SRC-PTK2B comple, Xenopus/Amphibian, and c-SRC kinase activity are necessary for this function. Once it is recruited to the activated integrins by PTK2Bovine, c-Src phosphorylates CBL which in turn induces the activation and recruitment of phosphatidylinositol 3-kinase to the cell membrane in a signaling pathway that is critical for osteoclast function. C-Src promotes energy production in osteoclasts by activating mitochondrial cytochrome C o, Xenopus/Amphibian,idase.

Catalogue number:	252767
Reactivities:	Human
Applications:	Western Blot
Size:	0.1 ml
Accession:	P12931
Antigen:	Purified recombinant fragment of SRC(aa10-193) e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG2b
Clonality:	4F1E8
Additional info:	SRC; Proto-oncogene tyrosine-protein kinase Src; pp60c-src; p60-Src; c-Src; SRC1