SRY (L80) pAb

Cat no: BS2037

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

SRY (sex-determining region Y protein) is a transcriptional activator required for male sex determination in mammals. This protein, also referred to as testis-determining factor (TDF), is an HMG box protein that initiates the formation of testis from undifferentiated gonad. The DNA-binding activity of SRY is required for normal testis formation. This DNA-binding activity is thought to be regulated by PKA, which phosphorylates SRY in vivo. Mutations in SRY have been associated with 46,XY gonadal dysgenesis, in which the gonads fail to develop in XY phenotypic females.

Catalogue number:	BS2037
Reactivities:	Human
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	Q05066
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 50-100 of Human SRY.
Species:	SRY (L80) pAb detects endogenous levels of SRY protein.
Molecular weight:	~ 37 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	SRY (Sex determining region Y)-box 13. isoform CRA_b; SOX13; RP11-74C13.1. ICA12. MGC117216. SRY-box 13. Sox-13
Additional info:	For research use only, not for use in diagnostic procedure.

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SRY (L80) pAb

Cat no: BS2037

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