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SSAT-1, Recombinant Human (AA617398, Diamine acetyltransferase 1, Polyamine N-acetyltransferase 1, Putrescine acetyltransferase, Sat, Spermidine/spermine N(1)-acetyltransferase 1, SSAT, SSAT-1, DC21, KFSD, KFSDX)

Cat no: S1099-16

SSAT-1, Recombinant Human (AA617398, Diamine acetyltransferase 1, Polyamine N-acetyltransferase 1, Putrescine acetyltransferase, Sat, Spermidine/spermine N(1)-acetyltransferase 1, SSAT, SSAT-1, DC21, KFSD, KFSDX)

Diamine N-acetyltransferase 1(or Spermidine/spermine-N1-acetyltransferase, SSAT1), as known as SAT-1, is a polyamine catabolic enzyme which catalyzes the acetylation of polyamines. This protein plays an important role in polyamine homoeostasis, since acetylated products are either excreted from the cell or oxidized by acetylpolyamine oxidase. A variety of other effects of increased SAT-1 activity include death of pancreatic cells, blockage of regenerative tissue growth, behavioral changes, keratosis follicularis spinulosa decalvans(KFSD), and hair loss. Recombinant human SAT-1, fused to His-tag at N-terminus, , expressed in E. coli and purified by using conventional chromatography.\n\nSource:\nRecombinant human Diamine N-acetyltransferase 1, aa1-171, His-tagged,, expressed in E. coli\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID \nKEYLLKMATE E\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S1099-16

Size

100ug

Form

Supplied as liquid in 20 mM Tris-HCl buffer, pH8.0, 10% glycerol

Purity

~95% by SDS-PAGE Purified by immunoaffinity chromatography.

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