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ST-2, Recombinant, Human (Interleukin-1 Receptor-like 1, Protein ST2, IL1RL1, DER4, ST2, T1)

Cat no: S6606-50S

ST-2, Recombinant, Human (Interleukin-1 Receptor-like 1, Protein ST2, IL1RL1, DER4, ST2, T1)

The ST2 gene is a member of the IL-1 receptor family, encoding a transmembrane protein with a structure similar to IL-1R1. A soluble form of the protein (ST2) is produced from the same gene by alternative splicing and is reported to be expressed in several cell types including fibroblasts and mast cells. Soluble ST2 has been reported to act as a negative regulator of Th2 cytokine production and elevated levels have been reported in several disease states and conditions including asthma, sepsis and myocardial infarction.\n\nSource: \nRecombinant corresponding to aa19-328 from human ST2, fused to 6x His-tag at N-terminal, expressed in E. coli.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S6606-50S

Size

10ug

Form

Supplied as liquid.

Purity

~95% (SDS-PAGE)

References

1. Trajkovic V et al., (2004) Cytokine Growth Factor Rev.15(2-3): 87- 95.

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