ST13 (3B10) Antibody

Cat no: 252945

Supplier: ABBIOTEC

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Description
Additional Information

ST13 (Suppression of tumorigenicity protein 13) is one of several co-chaperones that regulate activities of the HSP70 chaperone family. ST13, also known as Hip (HSP70-interacting protein) cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, also controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

Catalogue number:	252945
Reactivities:	Human, Mouse
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	P50502
Antigen:	Purified recombinant fragment of human ST13 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3B10
Additional info:	Hsc70-interacting protein; Hip; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; Suppression of tumorigenicity 13 protein; FAM10A1; HIP; SNC6; ST13