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Stachybotrylactam (2-deoxy Antibiotic F1839A)

Cat no: S6607


Supplier: United States Biological
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Isolated from a Stachybotrys sp., this unusual spirodihydrobenzofuranlactam mycotoxin shows immuno-suppressant and weak HIV protease activity. Members of this structural class show diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition. Purity: >95% by HPLC Solubility: Soluble in ethanol, methanol, DMF or DMSO.
Catalogue number: S6607
Size: 500ug
Purity: >95% by HPLC
Alternative names: 2-deoxy Antibiotic F1839A
References: 1. Total synthesis and structure revision of Stachybotrys spirolactams. Deng W.P. et al. J. Org. Chem. 2003, 68, 7422. 2. Novel spirodihydrobenzofuranlactams as antagonists of endothelin and as inhibitors of HIV-1 protease produced by Stachybotrys sp. I. Fermentation, isolation and biological activity. Roggo B.E. et al. J. Antibiot. 1996, 49, 13. 3. Stachybotrys toxins I. Jarvis B.B. et al. Nat. Toxins 1995, 3, 10.

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