Acidic proteins that regulate bone mineralization are abundant in bones and teeth. The acidic nature of these proteins makes them difficult to detect by conventional staining methods in SDS-PAGE gels. The Stain All Kit is specifically designed to stain strongly acidic proteins in SDS-PAGE gels. The color of the protein band varies depending on the isoelectric point (pI) of the protein and chemical modifications like glycosylation and phosphorylation.
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