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STAM-1, Recombinant, Human (HSE1 Homolog, STAM, Signal Transducing Adapter Molecule 1)

Cat no: 145835

STAM-1, Recombinant, Human (HSE1 Homolog, STAM, Signal Transducing Adapter Molecule 1)

STAM-1 (Signal Transducing Adapter Molecule 1) is involved in multiple signal transduction pathways through interactions mediated by ITAM, SH3, UIM, and VHS domains located within the protein. Roles in growth factor receptor down-regulation, T-cell development, and induction of DNA synthesis following IL-2 stimulation have been identified. This full-length recombinant protein has no intrinsic deubiquitinase activity, but is useful in stimulating the in vitro activity of the JAMM-class deubiquitinase AMSH.\n\nSource:\nRecombinant protein corresponding to human STAM-1.\n\nMolecular Weight: \n~59kD\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

145835

Size

50ug

Form

Supplied as a liquid in 50mM HEPES, pH 8.0, 200mM NaCl, 2mM DTT, 2mM EDTA.

Purity

~90% (SDS-PAGE)

References

1. Agromayor, M. and Martin-Serrano, J. (2006) J. Biol. Chem. 281:23083-23091. 2. Kim, M.S., et al (2006) Biochem. Biophys. Res Comm. 351:612-618. 3. McCullough, J., et al (2006) Current Biology 16:160-165. 4. Sato, Y., et al (2008) Nature 455:358-362.

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SUPPLIER INFO

Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info

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