STAT2 Antibody

Cat no: 251510

Supplier: ABBIOTEC

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Description
Additional Information

Signal transducer and activator of transcription 2 (STAT2) is a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a comple, Xenopus/Amphibian,, termed ISGF3 transcription factor, which enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Catalogue number:	251510
Reactivities:	Human, Mouse, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P52630
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human STAT2.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	STAT2; Signal transducer and activator of transcription 2; p113