STAT3 (3B5) Antibody

Cat no: 253081

Supplier: ABBIOTEC

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Description
Additional Information

STAT3 (Signal transducer and activator of transduction 3) is a transcription factor that binds to the interleukin-6 responsive elements located in the promoter regions of various acute-phase protein genes. STAT3 is activated by IL-31 receptor pathway. Active STAT3 consists in homodimers or heterodimers with family member STAT1 and serine phosphorylation is important for DNA-binding and transcriptional activities. Defects in STAT3 are the cause of hyperimmunoglobulin E recurrent infection syndrome (Job syndrome).

Catalogue number:	253081
Reactivities:	Human, Mouse
Applications:	Immunofluorescence, Immunohistochemistry
Size:	0.1 ml
Accession:	P40763
Antigen:	Purified recombinant fragment of human STAT3 e, Xenopus/Amphibian,pressed in E. coli.
Format:	Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type:	Mouse Monoclonal Antibody
Isotype:	Mouse IgG1
Clonality:	3B5
Additional info:	Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF